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What is this medicine?
NITISINONE (nit IS i none) slows the breakdown of tyrosine. It is used to treat a rare disease called hereditary tyrosinemia type I.
How should I use this medicine?
Follow the directions on the prescription label. The tablet may be dissolved in a specific amount of water and given in an oral syringe immediately before use. The tablet may also be crushed and mixed in a small amount of applesauce immediately before use. Take your medicine at regular intervals. Do not take your medicine more often than directed. Do not stop taking except on your doctor's advice.
Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for children as young as newborns for selected conditions, precautions do apply.
What side effects may I notice from receiving this medicine?
Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
changes in vision
eye pain, redness, sensitivity to light
general ill feeling or flu-like symptoms
loss of appetite, nausea
painful growths on hands, soles of feet
right upper belly pain
unusual bleeding or bruising
unusually weak or tired
yellowing of eyes, skin
Side effects that usually do not require medical attention (report these to your doctor or health care professional if they continue or are bothersome):
What may interact with this medicine?
Interactions are not expected.
What if I miss a dose?
If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
Where should I keep my medicine?
Keep out of the reach of children.
Store at room temperature between 20 and 25 degrees C (68 to 77 degrees F). Throw away any unused medicine after the expiration date.
What should I tell my health care provider before I take this medicine?
They need to know if you have any of these conditions:
an unusual or allergic reaction to nitisinone, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
What should I watch for while using this medicine?
Visit your doctor for regular check ups. You will need to have important blood work done while you are taking this medicine.
You will need to be on a special diet while taking this medicine. Talk to your health care provider about the foods you eat and the vitamins you take. Follow your diet carefully to limit your intake of tyrosine and phenylalanine.